// Tech-enabled growth, operated for you

Revenue advisory for sophisticated markets

Astris Partners builds demand engines for B2B companies with complex buyers: long cycles, layered stakeholders, six or seven figures on the line. We run it end to end; you stay focused on the business.

See if you qualify →

30 minutes, no pitch deck. If the math doesn't work, we say so on the call.

//01   Buyers sourced off-market, not from lists
//02   Success fee tied to milestones
//03   No contracts or NDAs to start
// Companies we've helped our clients close deals with
Pfizer
Merck
Novartis
Roche
Sanofi
Bayer
Eli Lilly
Amgen
AbbVie
AstraZeneca
Thermo Fisher
Vertex
CVS Health
Kaiser Permanente
Mount Sinai
NYU Langone
Stanford Medicine
Harvard Medical
Google
Microsoft
Amazon
Apple
PwC
Walmart
// Our 2025 in numbers
649%
outperformance of competitor results on average, based on independent audits
85%
of Fortune 500 companies booked
1,000+
qualified conversations with decision-makers
70+
B2B companies advised across seven sectors
8 figures
in sales pipeline built in 2025
// The problem

The ceiling is distribution

Most of our partners arrive with a proven product, growth capital, and a pipeline that still leans on referrals and the founder's calendar. The solutions they turn to were built for a different job: pushing high volumes of simple, transactional deals through short cycles. None of that survives a six- or seven-figure sale with five stakeholders.

Everyone's working the same list

Every vendor, every SDR team, every agency pulls from the same stale databases. Your competitors are emailing the same 2,000 contacts you are - and the buyers actually in motion aren't on the list at all.

Referral dependence

New business arrives through relationships, not through a channel you control.

No forecast

Next quarter's demand is a guess, which makes hiring and planning a gamble.

Founder-led selling

The founders are still the only people who can open doors, so pipeline moves at the pace of their calendar.

// What we do

A proprietary demand architecture, executed on your behalf

We call it ATLAS: the proprietary technology our team uses to test messaging programmatically and launch tightly targeted campaigns. Built around your buyers, run by operators, and accountable for one thing - qualified opportunities on your calendar.

//01

Intelligence & architecture

The signal layer is the product. Data engineers from Fortune 500 orgs build it around your mandate - funding, hiring, regulatory and switching signals that decide who you pursue while they're still invisible to your competitors.

//02

Distribution & validation

Brand-safe, multi-touch outreach - every reply qualified against your criteria before it reaches your team.

//03

Compounding performance

Every campaign feeds the next. Targeting and messaging get sharper, yield concentrates where it converts.

// Where the alternatives break

Why the usual fixes fail

Velocity playbooks

Built to maximize sends and opens, which means nothing to the handful of buyers who can actually sign.

In-house SDR builds

Months of hiring, training and management overhead before the first real meeting lands.

Generalist agencies

Run a $250K considered sale the way they run a $2K subscription, and senior buyers can tell.

No proprietary data

Everyone works off the same stale database, with no read on intent, account context, or what is actually happening inside the company.

// Why the usual fixes fail

Four ways to build demand. One survives a committee

Every alternative on this table works somewhere. None of them was designed for a $250K considered sale with five stakeholders and an eighteen-month cycle.

Astris · ATLASVelocity playbooksIn-house SDR buildGeneralist agency
Where buyers come fromOff-market signal layer built per mandate by Fortune 500 data engineersThe same purchased database as every vendor emailing your marketThe same purchased database as every vendor emailing your marketThe same purchased database as every vendor emailing your market
Built forSix- and seven-figure considered salesHigh-volume transactional dealsWhatever the first hire already knows$2K subscriptions
Time to first meeting3-4 weeksFast, but the meetings don't qualify3-6 months of hiring and training4-8 weeks
Who qualifies the replyWe do, against your criteria, before handoffNobody - volume is the metricA junior rep learning your marketAn account manager carrying six accounts
After the meetingFractional commercial lead, call reviews, assetsOut of scopeYour problemOut of scope
Commercial modelFixed component plus milestone success feePer-meeting, quality unenforcedSalary, ramp and management overheadFlat retainer regardless of outcome
// Track record · nine mandates on camera

Results from markets most firms avoid

Gatekept buyers, $1B+ conglomerates, deals years in the making - including conversations at 17 of the 20 largest US pharma organizations, buyers most vendors never get in front of. Our partners tell the story on camera, numbers included.

Diagnostics platform
100+
partner meetings in under 3 months

Alveo had spent two and a half years hunting co-development partners who matched six to eight characteristics at once - a dedicated team still described it as a needle in a haystack, with each partnership worth hundreds of thousands to millions. We booked over 100 meetings with strategic prospects inside three months. Many are now advancing toward formal agreements.

You guys have kind of thrown the switch magically, and it's a game changer for us. It's like you get it - and the ROI is just off the charts.Erik Tyrrell-Knott · VP Business Development, Alveo Technologies
Ex-GE Healthcare. Commercializing handheld molecular testing.
Anti-counterfeiting technology
8 wks
to Colgate, Ferrero, Merck and Tata

Counterfeiters target the largest organizations on earth, so Ennoventure needed lighthouse accounts at companies doing $500M+ in global revenue - buyers most vendors never get in front of. We fixed deliverability into the enterprise, workshopped the message until it landed, and set qualified meetings that became CRM opportunities.

Having Astris on our side - clearly being able to get the deliverability into the enterprise, being able to workshop the messaging, getting that feedback loop - was very helpful for us.Taylor Tresselt · Ennoventure
Ex-Oracle. Selling brand protection to $1B+ conglomerates.
Last-mile delivery technology
$250K
ARR - 7x their average customer

98% of Medzoomer's lead flow came from cold calling. Outbound was the one channel they could never crack: blacklisted domains from earlier attempts, pharmacy gatekeepers and procurement, and two to three vendors who had already failed at it. After a meticulous three-to-four week deliverability ramp they averaged three to five qualified calls a week - and closed the largest deal in company history.

I let go of the reins and let you do what you do best. We definitely have the ROI now to prove it was the right decision to trust your guidance.Marvin Kloss · Founder & CEO, Medzoomer
Built compliance-grade last-mile delivery for pharmacy.
SMB lending
$1.8M
in approvals generated in 45 days

Big Think Capital needed new lead channels for a 75-rep sales floor where every rep wants roughly 250 leads a month - and in SMB lending a new source has to prove itself fast, because the borrower needs financing inside 72 hours. The very first outbound message they replied to funded a deal. Inside 45 days we generated over $1.8M in approvals - from 154 leads against a forecast of 30 - with four businesses funded so far.

A brand-new lead source where the first lead funds and goes through the full process is a testament to your work.Jake Dombroski · Director, Big Think Capital
11 years in SMB lending fintech.
Medical device AI
~70
conversations booked in 5 months

Infera's outbound was conferences and LinkedIn, capped by how much time a lean founding team could spare - and their buyers are a narrow set of regulatory affairs leaders and CDMOs. A previous fractional hire took a month just to get systems started. We booked around 70 conversations, with dozens still live deep in pipeline after multiple meetings.

I've never had a conversation that is a waste of time. You can cast a wide net, but make sure you're fishing in the right part of the ocean.Harry Blumsack · Founder & CEO, Infera
Came out of medical device development; regulatory lead is ex-FDA.
Entertainment payroll
~90%
of meetings were real opportunities

Revolution Payroll had no outbound function at all - growth ran entirely on the founders' book of business - and in a union-heavy niche with only a handful of players in North America, Sukhi was certain nobody outside it could understand how it buys. We delivered market research and a 90-day plan before any contract was signed. Their funnel came up, meetings converted to customers, and they extended.

Every step of the way I was skeptical. Since then about 90% of the meetings have been legitimate opportunities - and we extended the contract.Sukhi Pabla · President & Co-Founder, Revolution Payroll
Builds payroll software for film, TV and commercial production.
Behavioral health
~50
calls booked across psychiatry practices

Mentavi ran cold outbound in-house for months, burning the time of the one business development rep they had - in a heavily regulated category where a category creator needs a challenger message. Corey evaluated a couple of dozen firms before signing. We onboarded with his whole bizdev and customer success team in the room, and the targeting got cleaner every cycle.

A lot of agencies in your position are more concerned about getting started than getting started right. That was really impressive.Corey Hart · Growth & Marketing, Mentavi Health
Eight years in mental health; third digital health company.
Herbal supplement retail
75-100
daily cold calls replaced

An in-house rep was dialing 75 to 100 numbers a day into a fragmented network of individual store owners who never pick up the phone, working from purchased lists that were outdated on arrival. We built real-time data on the actual decision-makers and reached them in writing instead - turning voicemails into sample requests and two-way conversations, then scaled once the formula held.

Astris was really good at slowing down to speed up. Once we got the formula right, we were able to explode and grow at scale.Colby Swann · 25+ years in revenue leadership
Cut his teeth at a Fortune 500 retailer.
Health tech
3-4 wks
to first results (in-house builds average 3-6 months)

This health-tech company was past the awareness phase and into hyper-growth, needing highly qualified prospects for a sophisticated offer - with finite startup resources and traditional outbound tooling that was quietly failing them. Three bespoke workshops and always-on message testing took what they already knew about their value proposition and fitted it to what qualified buyers actually needed - landing meetings with the Silicon Valley ICPs they were after in weeks rather than quarters.

There were so many blind spots, and it was very humbling for me as a CMO. I learned a lot from Kevin and his team.Christopher Gaube · Fractional CMO, Changent Brand
A decade at Nike; now fractional CMO to ~10 businesses.
// Straight from the inbox · 17 replies

Replies we wake up to

Real replies from live partner campaigns, exactly as they landed - senior people at the companies most vendors never reach. Names redacted, nothing else touched.

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Real replies from live partner campaigns, exactly as they landed. Names redacted, nothing else touched. Click any reply to zoom in.
Screenshots from live partner campaigns. Identities redacted for privacy; content otherwise untouched.

// Your fractional sales lead

We don't book conversations and disappear

Pipeline is only half the job. We stay on to help you convert it - acting as your fractional commercial lead, shaping the offer, and carrying the revenue target alongside you. Between our own mandates and our partners', we've sat in on thousands of sales conversations. We see what works in your industry every day - so we already know the shape your sales process needs to take.

Call review and coaching

We listen back with your team and fix what cost you the deal.

Assets that work in the room

The pre-call material your reps need to hold a senior buyer's attention.

A shorter route to signed

Fewer stalls between first conversation and closed deal.

// Who this is for

We don't specialize in a vertical. We specialize in a problem

The common thread across all of them is buyer complexity: long cycles, committees, gatekept inboxes, and the gap between where you are and where you need to be. That problem exists across dozens of industries and hundreds of sub-verticals.

Healthcare & Life Sciences

Health-tech, diagnostics, pharma services, medical platforms. Long, multi-stakeholder cycles. Compliance-sensitive outreach.

B2B Software & Data

Vertical SaaS, analytics, infrastructure, platforms post-PMF. Founder-led sales at a ceiling. Failed SDR builds.

Industrial, Manufacturing & Services

Authentication, supply chain, distribution, B2B services. Gatekept Fortune 500 buyers. No repeatable demand channel.

// The two questions we always get

What it costs, and what it breaks

“What does it cost?”

A fixed component plus a success fee, structured around milestones - and if we can't move the needle, we say so.

“What does my team have to change?”

Nothing. The engine runs in parallel with what you already have - your CRM, your tools and your team's workflow stay exactly as they are.

// Fit check

We're not a fit for everyone

We'd rather tell you now than three months in. If the offer isn't proven, the LTV is under $20K, the market is under 10,000 contacts, or you want a vendor at arm's length - the math doesn't work, and we'll say so on the first call.

//01

Proven demand

We amplify demand. We can't create it.

//02

$20K+ LTV

Below that, a precision-built meeting doesn't pay back.

//03

10,000+ addressable buyers

Message-market fit takes testing volume. We need a market big enough for the signal layer to work.

//04

Inside the tent

You see everything we do; we see everything you know.

// How it starts

From first call to qualified pipeline

//01

Tell us who you sell to

Who you sell to, your deal size, and where demand is stuck. Thirty minutes is enough to know whether the math works.

//02

We do the homework

We assess the opportunity and unit economics at no cost, then workshop what wins from your existing customers before anything is sent.

//03

Qualified conversations

The engine launches and vetted decision-makers start landing on your calendar - every outcome feeding the next campaign.

// Explore if we're a fit

Tell us about your market

If you'd rather just talk, book directly - 30 minutes, no pitch deck. Otherwise share where your demand comes from today and where it's stuck.

Every intro call includes a free custom Growth Plan - yours to keep either way.

  • //01 Response within 24 hours
  • //02 Thorough upfront diligence at no cost
  • //03 No contracts or NDAs required at this stage
  • //04 Your details stay between us
// Book directly

Pick a time

30 minutes, no pitch deck. You leave with a free custom Growth Plan for your market - and if the math doesn't work, we say so on the call.

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